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1

Acid-sensitive polyethylene glycol conjugates of doxorubicin: preparation, in vitro efficacy and intracellular distribution

Paula C.A. Rodrigues, Ulrich Beyer, Peter Schumacher, Thomas Roth, Heinz H. Fiebig, Clemens Unger, Luigi Messori, PierLuigi Orioli, Dietrich H. Paper, Rolf Mülhaupt, Felix Kratz

Journal:

Bioorganic & Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 362 KB

english, 1999

2

Uptake and bioavailability of anthocyanins and phenolic acids from grape/blueberry juice and smoothie in vitro and in vivo

Kuntz, Sabine, Rudloff, Silvia, Asseburg, Heike, Borsch, Christian, Fröhling, Bettina, Unger, Franziska, Dold, Sebastian, Spengler, Bernhard, Römpp, Andreas, Kunz, Clemens

Journal:

British Journal Of Nutrition

Year:

2015

Language:

english

File:

PDF, 1.64 MB

english, 2015

3

Besprechungen

M. v. Laue, Clemens Schaefer, E. Ungerer, A. Kratzer, W. Ludwig, H. Kienle, O. Koehler, H. Matthée, W. Rogowski, K. Zoller, W. Köster, H. Stille, v. Muralt, Gerhard Schramm, E. Waldschmidt-Leitz, Alfr

Journal:

Naturwissenschaften (The Science of Nature)

Year:

1944

Language:

german

File:

PDF, 1.89 MB

german, 1944

4

DCE-MRI assessment of the effect of vandetanib on tumor vasculature in patients with advanced colorectal cancer and liver metastases: a randomized phase I study

Klaus Mross, Ulrike Fasol, Annette Frost, Robin Benkelmann, Jan Kuhlmann, Martin Büchert, Clemens Unger, Hubert Blum, Jürgen Hennig, Tsveta P Milenkova, Jean Tessier, Annetta D Krebs, Anderson J Ryan,

Journal:

Year:

2009

Language:

english

File:

PDF, 1.14 MB

english, 2009

5

Treatment of Anthracycline Extravasation with Dexrazoxane – Clinical Experience

Frost, Annette, Gmehling, Daniela, Azemar, Marc, Unger, Clemens, Mross, Klaus

Journal:

Year:

2006

Language:

english

File:

PDF, 320 KB

english, 2006

6

Dietary supplementation with n-3-fatty acids in patients with pancreatic cancer and cachexia: marine phospholipids versus fish oil - a randomized controlled double-blind trial

Werner, Kristin, Küllenberg de Gaudry, Daniela, Taylor, Lenka A., Keck, Tobias, Unger, Clemens, Hopt, Ulrich T., Massing, Ulrich

Journal:

Lipids in Health and Disease

Year:

2017

Language:

english

File:

PDF, 1.16 MB

english, 2017

7

Vascular endothelial growth factor in the sera and effusions of patients with malignant and nonmalignant disease

Andrea Kraft, Karin Weindel, Andreas Ochs, Christian Marth, Jörg Zmija, Petra Schumacher, Clemens Unger, Dieter Marmé, Günther Gastl

Journal:

Year:

1999

Language:

english

File:

PDF, 155 KB

english, 1999

8

Psychosocial care for cancer patients: A new holistic psychosomatic approach in acute care and rehabilitation

Joachim Weis, Hans-Helge Bartsch, Gerd Arno Nagel, Clemens Unger

Journal:

Psycho-Oncology

Year:

1996

Language:

english

File:

PDF, 316 KB

english, 1996

9

Albumin Conjugates of the Anticancer Drug Chlorambucil: Synthesis, Characterization, and In Vitro Efficacy

Felix Kratz, Ulrich Beyer, Thomas Roth, Mark T. Schütte, Anuschka Unold, Heinz H. Fiebig, Clemens Unger

Journal:

Archiv der Pharmazie

Year:

1998

Language:

english

File:

PDF, 130 KB

english, 1998

10

Development of Albumin-binding Doxorubicin Prodrugs that are Cleaved by Prostate-specific Antigen

Felix Kratz, Ahmed Mansour, Jens Soltau, Andre Warnecke, Iduna Fichtner, Clemens Unger, Joachim Drevs

Journal:

Archiv der Pharmazie

Year:

2005

Language:

english

File:

PDF, 194 KB

english, 2005

11

Deprotonation of 5,6-Dihydro-5-methylene-4H-1,2-oxazines and Regioselective Reactions with Electrophiles

Clemens Unger, Reinhold Zimmer, Hans-Ulrich Reißig, Ernst-Ulrich Würthwein

Journal:

European Journal of Inorganic Chemistry

Year:

1991

Language:

english

File:

PDF, 768 KB

english, 1991

12

ChemInform Abstract: Synthesis and PLA2-Inhibitory Properties of 2(R)-Acetamidoalkylphosphomethanols (VIII) with a Variable Aggregate Anchor.

Joerg T. Kley, Guenter v. Kiedrowski, Clemens Unger, Ulrich Massing

Journal:

Year:

1999

File:

PDF, 31 KB

1999

13

Bemessungsmethode für eingefasstes Mauerwerk auf Grundlage des Eurocode 6

Dipl.-Ing. Dr. techn. Suikai Lu, Clemens Unger

Journal:

Year:

2010

Language:

german

File:

PDF, 186 KB

german, 2010

14

Synthesis and biological evaluation of an albumin-binding prodrug of doxorubicin that is cleaved by prostate-specific antigen (PSA) in a PSA-positive orthotopic prostate carcinoma model (LNCaP)

Ralph Graeser, Da-Eun Chung, Norbert Esser, Sandra Moor, Christoph Schächtele, Clemens Unger, Felix Kratz

Journal:

International Journal of Cancer

Year:

2008

Language:

english

File:

PDF, 518 KB

english, 2008

15

Correlation of the acid-sensitivity of polyethylene glycol daunorubicin conjugates with their in vitro antiproliferative activity

Paula C.A. Rodrigues, Thomas Roth, Heinz H. Fiebig, Clemens Unger, Rolf Mülhaupt, Felix Kratz

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 225 KB

english, 2006

16

Synthesis of two maleimide derivatives of cis-configurated platinum(II) complexes for the preparation of chemoimmunoconjugates

Mark Thomas Schütte, Peter Schumacher, Clemens Unger, Rolf Mülhaupt, Felix Kratz

Journal:

Inorganica Chimica Acta

Year:

1998

Language:

english

File:

PDF, 388 KB

english, 1998

17

Development and in vitro efficacy of novel MMP2 and MMP9 specific doxorubicin albumin conjugates

Felix Kratz, Joachim Drevs, Gerlinde Bing, Cornelia Stockmar, Karin Scheuermann, Peter Lazar, Clemens Unger

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 228 KB

english, 2001

18

Synthesis and In vitro efficacy of acid-Sensitive poly(ethylene glycol) paclitaxel conjugates

Paula C.A Rodrigues, Karin Scheuermann, Cornelia Stockmar, Gerhard Maier, Heinz H Fiebig, Clemens Unger, Rolf Mülhaupt, Felix Kratz

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 189 KB

english, 2003

19

Synthesis of new maleimide derivatives of daunorubicin and biological activity of acid labile transferrin conjugates

Felix Kratz, Ulrich Beyer, Peter Schumacher, Michael Krüger, Heike Zahn, Thomas Roth, Heinz H. Fiebig, Clemens Unger

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 385 KB

english, 1997

20

Synthesis and PLA2-inhibitory properties of 2(R)-acetamido-alkylphosphomethanols with a variable aggregate anchor

Jörg T. Kley, Günter v. Kiedrowski, Clemens Unger, Ulrich Massing

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 217 KB

english, 1999

21

Liposomal gemcitabine (GemLip)—efficient drug against hormone-refractory Du145 and PC-3 prostate cancer xenografts

Peter Jantscheff, Norbert Esser, Ralph Graeser, Vittorio Ziroli, Jessica Kluth, Clemens Unger, Ulrich Massing

Journal:

Year:

2009

Language:

english

File:

PDF, 329 KB

english, 2009

22

Aminoglutethimide

Clemens Unger, Hansjörg Eibl, Hans-Wulfard Heyden, Duck-Ja Kim, Gerhard Arno Nagel

Journal:

Investigational New Drugs

Year:

1986

Language:

english

File:

PDF, 257 KB

english, 1986

23

Alkylphosphocholines: influence of structural variation on biodistribution at antineoplastically active concentrations

Jochem Kötting, Martin R. Berger, Clemens Unger, Hansjörg Eibl

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1992

Language:

english

File:

PDF, 773 KB

english, 1992

24

Distribution of hexadecylphosphocholine and octadecyl-methyl-glycero-3-phosphocholine in rat tissues during steady-state treatment

Norbert Marschner, Jochem Kötting, Hansjörg Eibl, Clemens Unger

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1992

Language:

english

File:

PDF, 682 KB

english, 1992

25

Synthesis of Isosteric Phosphono Analogs of Biologically Active Alkylphosphocholines

Jörg T. Kley, Clemens Unger, Ulrich Massing

Journal:

Monatshefte für Chemie - Chemical Monthly

Year:

1998

Language:

english

File:

PDF, 279 KB

english, 1998

26

Pharmacokinetics of liposomal doxorubicin (TLC-D99; Myocet) in patients with solid tumors: an open-label, single-dose study

Klaus Mross, Bernward Niemann, Ulrich Massing, Joachim Drevs, Clemens Unger, Rupinder Bhamra, Christine E. Swenson

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2004

Language:

english

File:

PDF, 356 KB

english, 2004

27

Marine phospholipids—a promising new dietary approach to tumor-associated weight loss

Lenka A. Taylor, Lars Pletschen, Jann Arends, Clemens Unger, Ulrich Massing

Journal:

Supportive Care in Cancer

Year:

2010

Language:

english

File:

PDF, 311 KB

english, 2010

28

Fast reduction of undersampling artifacts in radial MR angiography with 3D total variation on graphics hardware

Florian Knoll, Markus Unger, Clemens Diwoky, Christian Clason, Thomas Pock, Rudolf Stollberger

Journal:

Magnetic Resonance Materials in Physics, Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 657 KB

english, 2010

29

Anti-metastatic effects of liposomal gemcitabine in a human orthotopic LNCaP prostate cancer xenograft model

Peter Jantscheff, Vittorio Ziroli, Norbert Esser, Ralph Graeser, Jessica Kluth, Alena Sukolinskaya, Lenka A. Taylor, Clemens Unger, Ulrich Massing

Journal:

Clinical and Experimental Metastasis

Year:

2009

Language:

english

File:

PDF, 368 KB

english, 2009

30

c-kit (CD117) Expression in Human Tumors and its Prognostic Value: An Immunohistochemical Analysis

Michael Medinger, Manuela Kleinschmidt, Klaus Mross, Barbara Wehmeyer, Clemens Unger, Hans-Eckart Schaefer, Renate Weber, Marc Azemar

Journal:

Pathology & Oncology Research

Year:

2010

Language:

english

File:

PDF, 281 KB

english, 2010

31

Transferrin conjugates of doxorubicin: Synthesis, characterization, cellular uptake, and in vitro efficacy

Felix Kratz, Ulrich Beyer, Thomas Roth, Nadya Tarasova, Philippe Collery, Francoise Lechenault, Annie Cazabat, Peter Schumacher, Clemens Unger, Ulrich Falken

Journal:

Journal of Pharmaceutical Sciences

Year:

1998

Language:

english

File:

PDF, 148 KB

english, 1998

32

Differences in the Intracellular Distribution of Acid-Sensitive Doxorubicin-Protein Conjugates in Comparison to Free and Liposomal Formulated Doxorubicin as Shown by Confocal Microscopy

Ulrich Beyer, Barbara Rothen-Rutishauser, Clemens Unger, Heidi Wunderli-Allenspach, Felix Kratz

Journal:

Pharmaceutical Research

Year:

2001

Language:

english

File:

PDF, 5.17 MB

english, 2001

33

Current concepts of treatment in medical oncology: new anticancer drugs

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

1996

Language:

english

File:

PDF, 967 KB

english, 1996

34

Effects of antineoplastic phospholipids on parameters of cell differentiation in U937 cells

Christa Hochhuth, Dinko Berkovic, Hansjörg Eibl, Clemens Unger, Detlef Doenecke

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

1990

Language:

english

File:

PDF, 1.26 MB

english, 1990

35

A continuous assay forO-alkylglycerol monooxygenase (E.C. 1.14.16.5)

Jochem Koetting, Clemens Unger, Hansjoerg Eibl

Journal:

Year:

1987

Language:

english

File:

PDF, 570 KB

english, 1987

36

Cytotoxic effects of ether lipids and derivatives in human nonneoplastic bone marrow cells and leukemic cells in vitro

Hans D. Schick, Wolfgang E. Berdel, Michael Fromm, Ulrich Fink, Ulrich Jehn, Kurt Ulm, Anneliese Reichert, Hansjörg Eibl, Clemens Unger, Johann Rastetter

Journal:

Year:

1987

Language:

english

File:

PDF, 553 KB

english, 1987

37

Foreword

Hansjörg Eibl, Clemens Unger

Journal:

Year:

1987

Language:

english

File:

PDF, 50 KB

english, 1987

38

Effect of synthetic phospholipids on platelet aggregation and serotonin release

Ulrike Söling, Hansjörg Eibl, Gerd A. Nagel, Clemens Unger

Journal:

Year:

1987

Language:

english

File:

PDF, 253 KB

english, 1987

39

Substrate specificity ofO-alkylglycerol monooxygenase (E.C. 1.14.16.5), solubilized from rat liver microsomes

Jochem Kötting, Clemens Unger, Hansjörg Eibl

Journal:

Year:

1987

Language:

english

File:

PDF, 517 KB

english, 1987

40

Investigations on the cellular uptake of hexadecylphosphocholine

Eduard A. M. Fleer, Dinko Berkovic, Hansjoerg Eibl, Clemens Unger

Journal:

Year:

1993

Language:

english

File:

PDF, 784 KB

english, 1993

41

Ether lipid derivatives: Antineoplastic activity in vitro and the structure-activity relationship

Wolfgang E. Berdel, Daniel D. Von Hoff, Clemens Unger, Hans D. Schick, Ulrich Fink, Anneliese Reichert, Hansjorg Eibl, Johann Rastetter

Journal:

Year:

1986

Language:

english

File:

PDF, 450 KB

english, 1986

42

Hexadecylphosphocholine: Preclinical and the first clinical results of a new antitumor drug

Clemens Unger, Hansjörg Eibl

Journal:

Year:

1991

Language:

english

File:

PDF, 670 KB

english, 1991

43

Hexadecylphosphocholine induces interferon-γ secretion and expression of GM-CSF mRNA in human mononuclear cells

Christa H. Hochhuth, Katalin Vehmeyer, Hansjörg Eibl, Clemens Unger

Journal:

Cellular Immunology

Year:

1992

Language:

english

File:

PDF, 1.07 MB

english, 1992

44

Impact of body mass index on the outcome of patients with multivessel disease randomized to either coronary artery bypass grafting or stenting in the ARTS trial: The obesity paradox II?

Luis Gruberg, Nestor Mercado, Simcha Milo, Eric Boersma, Clemens Disco, Gerrit-Anne van Es, Pedro A. Lemos, Margalit Ben Tzvi, William Wijns, Felix Unger, Rafael Beyar, Patrick W. Serruys

Journal:

The American Journal of Cardiology

Year:

2005

Language:

english

File:

PDF, 159 KB

english, 2005

45

Vascular endothelial growth factor receptor tyrosine kinase inhibitors: PTK787/ZK 222584

Anne L. Thomas, Bruno Morgan, Joachim Drevs, Clemens Unger, Bertram Wiedenmann, Udo Vanhoefer, Dirk Laurent, Margaret Dugan, William P. Steward

Journal:

Seminars in Oncology

Year:

2003

Language:

english

File:

PDF, 279 KB

english, 2003

46

Specific Protein Phosphorylation during Stimulation of Amylase Secretion by β-Agonists or Dibutyryl Adenosine 3′,5′-Monophosphate in the Rat Parotid Gland

Reinhard JAHN, Clemens UNGER, Hans-Dieter SÖLING

Journal:

Year:

1980

Language:

english

File:

PDF, 777 KB

english, 1980

47

In vitro and in vivo Efficacy of Acid-Sensitive Transferrin and Albumin Doxorubicin Conjugates in a Human Xenograft Panel and in the MDA-MB-435 Mamma Carcinoma Model

Kratz, Felix, Roth, Thomas, Fichiner, Iduna, Schumacher, Peter, Fiebig, Heinz, Unger, Clemens

Journal:

Journal of Drug Targeting

Year:

2000

Language:

english

File:

PDF, 884 KB

english, 2000

48

Synthetic phospholipids as substrates for phospholipase C from Bacillus cereus

Uwe Ries, Eduard A.M. Fleer, Clemens Unger, Hansjörg Eibl

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1992

Language:

english

File:

PDF, 610 KB

english, 1992

49

Is protein carboxymethylation involved in stimulus—secretion coupling?

Clemens Unger, Reinhard Jahn, Hans-Dieter Söling

Journal:

Year:

1981

Language:

english

File:

PDF, 354 KB

english, 1981

50

Phase I clinical and pharmacokinetic study of PTK/ZK, a multiple VEGF receptor inhibitor, in patients with liver metastases from solid tumours

Klaus Mross, Joachim Drevs, Marianne Müller, Michael Medinger, Dieter Marmé, Jürgen Hennig, Bruno Morgan, David Lebwohl, Eric Masson, Yu-Yun Ho, Clemens Günther, Dirk Laurent, Clemens Unger

Journal:

European Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 152 KB

english, 2005

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